331 MATERNAL-FETAL TRANSFER OF MELATONIN IN THE NONHUMAN PRIMATE
نویسندگان
چکیده
منابع مشابه
Cocaine is pharmacologically active in the nonhuman primate fetal brain.
Cocaine use during pregnancy is deleterious to the newborn child, in part via its disruption of placental blood flow. However, the extent to which cocaine can affect the function of the fetal primate brain is still an unresolved question. Here we used PET and MRI and show that in third-trimester pregnant nonhuman primates, cocaine at doses typically used by drug abusers significantly increased ...
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The nonhuman primate brain, the model system closest to the human brain, plays a critical role in our understanding of neural computation, cognition, and behavior. The continued quest to crack the neural codes in the monkey brain would be greatly enhanced with new tools and technologies that can rapidly and reversibly control the activities of desired cells at precise times during specific beha...
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Offspring produced by nuclear transfer (NT) have identical nuclear DNA (nDNA). However, mitochondrial DNA (mtDNA) inheritance could vary considerably. In sheep, homoplasmy is maintained since mtDNA is transmitted from the oocyte (recipient) only. In contrast, cattle are heteroplasmic, harboring a predominance of recipient mtDNA along with varying levels of donor mtDNA. We show that the two nonh...
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Infection with Listeria monocytogenes during pregnancy is associated with miscarriage, preterm birth, and neonatal complications, including sepsis and meningitis. While the risk of these conditions is thought to be greatest during the third trimester of pregnancy, the determinants of fetoplacental susceptibility to infection, the contribution of gestational age, and the in vivo progression of d...
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Gravid macaques (n=12) were maintained on a control diet (14% calories from fat, n=4) or a high fat diet (36% calories from fat, n = 8). On gestational day 129, the macaques were injected with ProHance gadolinium contrast for placental imaging (equivalent to the third trimester). Gadolinium dose was varied based on maternal weight, using 0.1 mmol/kg dosing. Fetuses were delivered via cesarean s...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1978
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197804001-00336